Related Conditions
Understanding associated autoimmune disorders
In One Minute
Coeliac disease is often associated with other autoimmune conditions. People with celiac disease have a higher risk of developing Type 1 diabetes, autoimmune thyroid disease, autoimmune liver disease, and other conditions. First-degree relatives of people with celiac disease should be screened. If you have celiac disease and experience new symptoms, discuss screening for related conditions with your healthcare provider.
Common Associated Conditions
Type 1 Diabetes
5-10% of people with Type 1 diabetes also have celiac disease. Regular screening is recommended for diabetic patients.
Screening: At diagnosis and periodically thereafter
Autoimmune Thyroid Disease
Hashimoto's thyroiditis and Graves' disease occur more frequently in people with celiac disease.
Screening: If symptoms of thyroid dysfunction develop
Dermatitis Herpetiformis
A skin manifestation of celiac disease characterized by intensely itchy, blistering rash. Responds to a gluten-free diet.
Screening: Skin biopsy for diagnosis
Autoimmune Liver Disease
Includes autoimmune hepatitis and primary biliary cholangitis. Elevated liver enzymes may be the only sign.
Screening: Regular liver function tests
Chromosomal Conditions
Certain genetic conditions are associated with higher rates of celiac disease:
Down Syndrome
12-16% of individuals with Down syndrome have celiac disease. Regular screening is recommended.
Turner Syndrome
4-8% of individuals with Turner syndrome have celiac disease. Screening should be performed.
Family Screening
First-degree relatives (parents, siblings, children) of people with celiac disease have a 10-15% chance of also having the condition.
Screening Recommendations:
- All first-degree relatives should be tested, even without symptoms
- Testing should include celiac antibody blood tests
- Consider genetic testing (HLA-DQ2/DQ8) to help assess risk
- Repeat testing every 2-3 years if initial tests are negative
Important Note
If you have celiac disease and develop new symptoms or have a family history of autoimmune conditions, discuss appropriate screening with your healthcare provider. Early detection and management of related conditions can prevent complications.
Related Conditions Resources
Authoritative organisations providing evidence-based information and support for coeliac disease.
Information on conditions commonly associated with coeliac disease.
United KingdomResearch and resources on autoimmune conditions linked to celiac disease.
United StatesInternational scientific society research on coeliac disease comorbidities.
InternationalNote: External links are provided for informational purposes. We are not responsible for the content of external websites. Always consult healthcare professionals for medical advice.